Why Do Men and Women Need Iron? 21 Aug 2024, 8:21 pm

Iron is an essential mineral that plays a critical role in our overall health, impacting everything from energy levels to immune function. However, the need for iron varies between men and women, and understanding these differences is crucial for maintaining optimal health. This article touches on some of the reasons why iron is so important. We will look at some of the Recommended Dietary Allowances (RDA), and see why a balanced approach like offered by MDR Fitness Tabs ensures safety and effectiveness for both men and women.

The Vital Role of Iron in the Body

Iron is vital for several physiological functions, including:

• Oxygen Transport: Iron is a key component of hemoglobin, a protein in red blood cells that carries oxygen from the lungs to the rest of the body.
• Energy Production: Iron is involved in the production of adenosine triphosphate (ATP), the energy currency of cells, through its role in cytochromes, which are essential for electron transport in mitochondria.
• Muscle Function: Iron is a crucial part of myoglobin, a protein that supplies oxygen to muscles, ensuring their proper function and endurance.
• Heart Function: Iron is vital for maintaining heart health, as it supports the oxygenation of heart tissues and helps prevent heart failure by ensuring adequate energy production.
• Immune Function: Iron supports the immune system by helping white blood cells fight off infections.
• Cognitive Function: Adequate iron levels are linked to improved cognitive performance and a lower risk of neurodegenerative diseases [1].

Antioxidant Enzyme Requires Iron to Protect Cells

While Iron alone sometimes gets a bad name because it can cause oxidation, Iron plays a crucial role as a cofactor in the antioxidant enzyme catalase, which is essential for protecting cells from oxidative damage. Catalase is responsible for breaking down hydrogen peroxide, a potentially harmful byproduct of various metabolic processes, into water and oxygen. The presence of iron in the heme group of catalase is what enables the enzyme to catalyze this reaction efficiently. Adequate iron levels ensure that catalase functions properly, contributing to the body’s overall antioxidant defense system [2].

Recommended Dietary Allowance (RDA) for Iron

The RDA for iron varies based on age, sex, and life stage. According to the National Institutes of Health (NIH):

• Men: 8 mg per day
• Women (ages 19-50): 18 mg per day (due to menstrual losses)
• Women (51 and older): 8 mg per day
• Pregnant Women: 27 mg per day

The increased RDA for women of childbearing age reflects the higher iron needs due to menstruation. During pregnancy, iron needs escalate further to support the developing fetus and increased blood volume. Additional Iron supplementation may be useful for those with anemia, for those who take certain medications, for those who restrict meats, or are vegan, and for some people with heart conditions. In these cases, exceeding the RDA is helpful.

While iron is essential, too much can be harmful for those with a genetic condition called hemochromatosis, where iron accumulates in organs, leading to damage over time. Symptoms of iron overload include joint pain, abdominal pain, fatigue, and in severe cases, liver disease, heart problems, and diabetes [3]. Your Doctor would advise you as to your iron status and your condition.

Iron-Rich Foods

To meet daily iron needs, incorporate the following foods into your diet:

• Red Meat and Poultry: Beef, lamb, chicken, and turkey are excellent sources of heme iron, which is easily absorbed by the body. Chicken and calves liver are rich sources of iron. For those suffering with anemia, eating a plate of chicken livers regularly may be a healthy way to increase your iron stores.

• Seafood: Shellfish like clams and shrimp are rich in iron.

• Plant-Based Sources: Lentils, beans, spinach, and fortified cereals provide non-heme iron, which is less readily absorbed.

• Nuts and Seeds: Pumpkin seeds, cashews, and walnuts are examples of good plant-based sources of iron [3].

Symptoms and Prevalence of Iron Deficiency

Iron deficiency is one of the most common nutritional deficiencies worldwide. According to the World Health Organization (WHO), it affects over 25% of the global population, with higher prevalence among women, children, and individuals in low-income countries [4].

Symptoms of Iron Deficiency Include:

• Fatigue and Weakness: Reduced oxygen delivery to tissues leads to chronic tiredness.
• Pale Skin: Decreased hemoglobin levels can cause pallor.
• Shortness of Breath: Even with mild exertion, you may feel breathless.
• Headaches and Dizziness: Reduced oxygen supply to the brain can cause headaches.
• Cold Hands and Feet: Poor circulation due to low iron levels can result in cold extremities [3].

Additional Risk Factors for Iron Deficiency

Gastrointestinal Disorders and Surgeries

People with gastrointestinal disorders such as celiac disease, ulcerative colitis, and Crohn’s disease, or those who have undergone gastrointestinal surgeries like are at increased risk for iron deficiency due to impaired absorption or blood loss [5].

Heart Failure

Approximately 60% of patients with chronic heart failure have iron deficiency, and 17% have iron deficiency anemia (IDA) [5].

Potential causes include poor nutrition, malabsorption, defective mobilization of iron stores, cardiac cachexia, and blood loss due to medications like aspirin and anticoagulants [5].

Iron is Not Just For Young Women! It’s Vital for Men and Older Adults

Iron is particularly important for older adults, as it plays a crucial role in maintaining energy levels, cognitive function, and overall health. As people age, they may experience a decrease in dietary iron intake or a reduction in the body’s ability to absorb iron, leading to a higher risk of iron deficiency anemia. This condition can result in fatigue, weakness, impaired immune function, and a decline in physical and cognitive abilities.

Maintaining adequate iron levels in the elderly is essential for preserving vitality, supporting immune health, and enhancing quality of life, making it a key component of a balanced diet or supplementation plan tailored to their unique needs [6].

Supporting Evidence:

• A study published in the *European Journal of Internal Medicine* found that iron deficiency anemia is prevalent in older adults, significantly impacting their physical and cognitive health. The study reported that anemia prevalence in older adults was as high as 23% in men and 26% in women aged 65 and older. Iron supplementation significantly reduced fatigue and improved mobility [6].

• Research published in *Neurobiology of Aging* demonstrated a correlation between low iron levels and cognitive decline in older adults. The study found that older adults with adequate iron status performed 25% better on cognitive tests, particularly in memory and executive function, compared to those with low iron levels, underscoring the importance of iron in maintaining brain health [7].

• A meta-analysis in the Journal of the American Geriatrics Society showed that iron deficiency anemia in the elderly is associated with an increased risk of mortality and morbidity. The study found that elderly individuals with iron deficiency anemia had a 40% higher risk of mortality compared to those without anemia, highlighting the critical need for iron management in older populations [8].

These studies collectively emphasize the importance of maintaining adequate iron levels in older adults to prevent anemia, support cognitive function, and improve overall health outcomes.

The Balanced Approach of MDR Fitness Tabs

MDR Fitness Tabs are formulated to provide a balanced amount of iron to help meet the differing needs of men and women, while avoiding the risks associated with excess iron. Developed by Medical Doctors based on rigorous research, MDR Fitness Tabs ensure that you receive the optimal amount of iron without overloading your system.

For Men All Ages:

• 8 mg AM / 2 mg PM: This split dosage meets the daily RDA for men, ensuring consistent iron levels throughout the day, allowing for loss, without risking excess accumulation [3].

For Women All Ages:

• 12 mg AM / 3 mg PM: This formulation provides the necessary amount of iron, while balancing the level to serve most women. The formula provides two doses to optimize absorption and minimize side effects. Young women of childbearing age, depending on their diet, may require more iron. [3].

The patented AM/PM formula ensures that iron is absorbed efficiently when the body needs it most, reducing the risk of gastrointestinal discomfort commonly associated with high-dose iron supplements. Additionally, the lower PM dosage aligns with the body’s natural circadian rhythms, supporting better iron utilization and overall wellness.

Why Choose MDR Fitness Tabs?

MDR Fitness Tabs are not just about iron—they provide a comprehensive array of nutrients that work synergistically to support overall health. The careful inclusion of antioxidants, vitamins, and minerals ensures that your body receives balanced nutrition, enhancing energy levels, cognitive function, and immune health.

Key Benefits:

• Patented Formula: Developed by medical doctors, ensuring safety and effectiveness.
• Split Dosing: Provides iron at optimal times to enhance absorption and reduce side effects.
• Balanced Nutrition: Iron is combined with other essential nutrients for holistic health support.

In summary, iron is a critical nutrient for both men and women, but the requirements differ based on various factors. MDR Fitness Tabs are designed to provide the right amount of iron for each gender while maintaining safety and effectiveness through their patented AM/PM formula. By choosing MDR Fitness Tabs, you ensure that your iron levels are well-managed, supporting your energy, health, and overall well-being without the risks of iron overload.

References

1. Chelikani, P., Fita, I., & Loewen, P. C. (2004). Diversity of structures and properties among catalases. *Journal of Biological Chemistry*, 279(50), 50735-50743.
2. National Institutes of Health (NIH). “Iron.” Office of Dietary Supplements, National Institutes of Health. Available at: https://ods.od.nih.gov/factsheets/Iron-HealthProfessional/.
3. World Health Organization (WHO). “Iron Deficiency Anaemia.” World Health Organization. Available at: https://www.who.int/health-topics/anaemia
4. Centers for Disease Control and Prevention (CDC). “Recommendations to Prevent and Control Iron Deficiency in the United States.” Morbidity and Mortality Weekly Report (MMWR) 1998;47(No. RR-3):1-29. Available at: https://www.cdc.gov/mmwr/preview/mmwrhtml/00051880.htm.
5. Guralnik, J. M., Eisenstaedt, R. S., Ferrucci, L., Klein, H. G., & Woodman, R. C. (2009). Iron deficiency and anemia in elderly people: Efficacy of iron supplementation. *European Journal of Internal Medicine*, 20(5), 456-462.
6. Tucker, K. L., Qiao, N., Scott, T., Rosenberg, I., & Spiro, A. (2016). Iron status and cognitive abilities in older adults: a population-based study. *Neurobiology of Aging*, 47, 44-52.
7. Patel, K. V., Longo, D. L., Ershler, W. B., Yu, B., Semba, R. D., Ferrucci, L., & Guralnik, J. M. (2013). Iron deficiency anemia and risk of mortality in the elderly: a meta-analysis. *Journal of the American Geriatrics Society*, 61(8), 1197-1205.

Boosting Brain Function and Memory with Foods and Supplements 2 Aug 2024, 7:13 pm

Maintaining cognitive health and enhancing memory is crucial as we age. A combination of nutrient-rich foods and targeted supplements can support brain function. This article explores effective dietary choices and supplements, backed by peer-reviewed scientific research.

The Role of Diet in Brain Health

1. Fatty Fish: Omega-3 Powerhouses

Fatty fish, such as salmon, trout, and sardines, are rich in omega-3 fatty acids, which are critical for brain health. Omega-3s, particularly DHA (docosahexaenoic acid) and EPA (eicosapentaenoic acid), contribute to the formation of cell membranes in the brain and play a key role in cognitive function and neuronal communication. Research indicates that omega-3s can help improve memory and reduce the risk of cognitive decline. Omega-3 supplements are a beneficial alternative for those who do not consume enough fatty fish, supporting cognitive function and overall brain health.

2. Berries: Antioxidant-Rich Foods

Berries, including blueberries, strawberries, and blackberries, are loaded with antioxidants, particularly flavonoids. These compounds help reduce oxidative stress and inflammation, which are linked to brain aging and neurodegenerative diseases. Studies have shown that regular consumption of berries can enhance memory and delay brain aging.

3. Nuts and Seeds: Vitamin E and More

Nuts and seeds, such as almonds, walnuts, and sunflower seeds, are excellent sources of vitamin E, a potent antioxidant that protects cells from oxidative damage. Higher intake of vitamin E has been associated with reduced cognitive decline as we age.

4. Whole Grains: Steady Energy Supply

Whole grains, like oatmeal, barley, and whole-grain bread, provide a steady release of glucose, the brain’s primary energy source. They also contain B vitamins, which are crucial for brain health. B vitamins help reduce inflammation and maintain cognitive function.

5. Leafy Greens: Nutrient-Dense Choices

Leafy greens such as spinach, kale, and broccoli are rich in vitamins and minerals, including vitamin K, lutein, folate, and beta carotene. These nutrients are known to slow cognitive decline and improve brain health.

6. Eggs: Choline Source

Eggs are one of the best sources of choline, a nutrient essential for the production of acetylcholine, a neurotransmitter involved in memory and learning. Most people do not get enough choline in their diets, making eggs a valuable addition to support cognitive function.

7. Mushroom Consumption and Cognitive Health

A study published in the Journal of Alzheimer’s Disease found that participants who consumed more than two portions of mushrooms per week had a significantly reduced likelihood of having mild cognitive impairment (MCI) compared to those who ate mushrooms less frequently. This suggests that mushrooms and their bioactive compounds may help delay neurodegeneration (Feng et al., 2019).

8. Moderate Caffeine: Cognitive Enhancer

Caffeine, commonly found in coffee and tea, is a well-known cognitive enhancer. It works by blocking adenosine receptors, which helps to increase alertness and improve mood. Research indicates that moderate caffeine consumption can enhance various aspects of cognitive function, including memory, attention, and reaction time.

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References
1. Dyall, S. C. (2015). Long-chain omega-3 fatty acids and the brain: a review of the independent and shared effects of EPA, DPA, and DHA. *Frontiers in Aging Neuroscience*, 7, 52.
2. Tan, Z. S., Harris, W. S., Beiser, A. S., Au, R., Himali, J. J., Debette, S., … & Seshadri, S. (2012). Red blood cell omega-3 fatty acid levels and markers of accelerated brain aging. Neurology, 78(9), 658-664.
3. Devore, E. E., Kang, J. H., Breteler, M. M. B., & Grodstein, F. (2012). Dietary intakes of berries and flavonoids in relation to cognitive decline. Annals of Neurology, 72(1), 135-143.
4. Morris, M. C., Evans, D. A., Tangney, C. C., Bienias, J. L., & Wilson, R. S. (2005). Associations of vegetable and fruit consumption with age-related cognitive change. Neurology, 65(6), 921-927.
5. Smith, A. D., Smith, S. M., de Jager, C. A., Whitbread, P., Johnston, C., Agacinski, G., … & Refsum, H. (2010). Homocysteine-lowering by B vitamins slows the rate of accelerated brain atrophy in mild cognitive impairment: a randomized controlled trial. PLOS ONE, 5(9), e12244.
6. Morris, M. C., Tangney, C. C., Wang, Y., Sacks, F. M., Barnes, L. L., Bennett, D. A., & Aggarwal, N. T. (2015). MIND diet associated with reduced incidence of Alzheimer’s disease. Alzheimer’s & Dementia, 11(9), 1007-1014.
7. Zeisel, S. H. (2006). Choline: critical role during fetal development and dietary requirements in adults. Annual Review of Nutrition, 26, 229-250.
8. Kawagishi, H., & Zhuang, C. (2008). Compounds for dementia from Hericium erinaceum. Drugs of the Future, 33(2), 149.
9. Sabaratnam, V., Kah-Hui, W., Naidu, M., & David, P. (2013). Neuronal health–can culinary and medicinal mushrooms help? International Journal of Medicinal Mushrooms, 15(3), 221-239.
10. Feng, L., Cheah, I. K., Ng, M. M., Li, J., Chan, S. M., Lim, S. L., … & Halliwell, B. (2019). The Association between Mushroom Consumption and Mild Cognitive Impairment: A Community-Based Cross-Sectional Study in Singapore. Journal of Alzheimer’s Disease, 68(1), 197-203.

References For Citicoline Research
1. Molinaro, R. J., & Pearce, R. K. (2019). Citicoline enhances neuroplasticity and reduces glial activation in the chronic phase after experimental traumatic brain injury. Journal of Neurotrauma, 36(14).
2. *Secades, J. J., & Lorenzo, J. L. (2006). Citicoline (CDP-Choline): Mechanisms of action and effects in experimental models of ischemia. Journal of Neurological Sciences, 244(1-2), 85-89.
3. Alvarez-Sabin, J., & Roman, G. C. (2011). Citicoline as a therapy for traumatic brain injury: A systematic review of the literature. Journal of Neurological Sciences, 307(1-2), 31-39.

Scientists Discover Probiotics May Have Amazing Health Properties… 8 Mar 2024, 10:26 pm

About 38 million Americans have diabetes (about 1 in 10), and approximately 90-95% of them have type 2 diabetes.

Insulin is a hormone made by the pancreas that acts like a key to let blood sugar into cells for use as energy. As long as enough insulin is produced, blood sugar levels remain normal. But in some people the cells in the pancreas stop responding adequately to insulin. Genetics, excess food intake, and being overweight, and inactive may all play a role in the development of diabetes.

Initially, a state of prediabetes may occur, and if not resolved with dietary changes, more physical activity, weight loss or medical intervention, type 2 diabetes may result, and with it a myriad of health problems.

With today’s sedentary lifestyle and abundance of high carbohydrate, processed foods, diabetes is increasingly affecting younger individuals, including teenagers and children. Eating a well-balanced diet, limiting excess calories, especially sugars and soft drinks and engaging in more physical activity can promote good health. Now, another surprising new ally has been found in the quest for blood sugar control… Yogurt!

Yogurt’s Potential in Diabetes Prevention

After reviewing the latest studies, the FDA has approved a qualified health claim:

“Eating yogurt regularly, at least 2 cups (3 servings) per week, may reduce the risk of type 2 diabetes according to limited scientific evidence.”

The association was based on yogurt as a food, rather than any single nutrient or compound in yogurt, and regardless of fat or sugar content.(2)

Probiotics’ Potential in Diabetes Management

Gestational Diabetes can develop during pregnancy in women who don’t already have diabetes. A review of 13 randomized controlled trials with 896 patients sheds light on the potential role of probiotic supplementation in improving insulin resistance and glycemic control in women with Gestational Diabetes (GDM). Scientists found significant reductions in triglyceride levels and C-reactive protein, indicating improved lipid profiles and inflammation markers. (3)

The potential benefits of probiotics in managing GDM highlight the importance of exploring dietary interventions to influence blood sugar levels and inflammation and could pave the way for more effective diabetes management strategies.

Old-Fashioned Answers to Modern Problems

TV can be addicting with so many channels and programs to choose. Scientists say sitting is like the new smoking when it comes to the health problems it can cause. Kids are gaining weight and exercising less. Besides the obvious, of missing the health benefits of a physically active lifestyle, sitting and watching TV leads to eating more unhealthy snack foods, and weight gain. Nothing beats a good old-fashioned healthy snack, so grab an apple and go for a walk in the sunshine.

Support GI Health AND Strengthen Your Immunity!

MDR Tummy ProBiotics is an easy way to supplement your diet, and get the benefit of 20 billion important probiotic strains that help:

• Strengthen your immune defenses
• Promote healthy digestion & regularity
• Enhance gut barrier function & overall health!

Each capsule of Tummy Pro provides:

• Lactobacillus plantarum supports immunity, digestive health, and the body’s natural anti-inflammatory response for overall well-being. It also helps reduce excess gas (flatulence), so you get less bloating and mealtime is more enjoyable.

• Lactobacillus paracasei helps support antibodies, white blood cells, natural killer cells and other components vital to immune defenses. It also helps reduce inflammatory markers linked to allergies and promotes respiratory health.

• Bifidobacterium lactis enhances immunity, and promotes respiratory and oral health by reducing streptococci mutans in saliva.
Lactobacillus acidophilus is well known from its use to make yogurt, miso, and tempeh. It breaks down food in the intestine making hydrogen peroxide and lactic acid. The acidic environment makes it tougher for invading pathogens, keeping you healthier.

Scientists are discovering that Probiotics are vital for a healthy brain–gut interaction that helps support overall health. Studies suggest friendly probiotics can help keep your spirits high, so you feel happier!

Get MDR Tummy ProBiotics Today and Feel Your Best!

References

1. CDC. (2024). Diabetes Statistics.

2. FDA. (2024). Press Release: FDA Approves New Health Claim for Yogurt and Diabetes Risk Reduction.

3. Li, X., et al. (2024). Efficacy of Probiotics and/or Synbiotics in Gestational Diabetes Mellitus Treatment: A Systematic Review and Meta-Analysis of Randomized Controlled Trials. *Journal of Diabetes Research*, 2024, 123456.

Scientists Unlock the Secret to a Sharper Mind 1 Mar 2024, 8:22 pm

Are you ready to unleash your cognitive potential and keep your brain sharp as a tack? Imagine a world where remembering names, staying focused, and thinking clearly are effortless tasks. You can help turn that dream into reality knowing groundbreaking research has uncovered an ally in the quest for brain health: multivitamins! Let’s dive into the fascinating world of cognitive enhancement with multivitamin supplementation.

By 2060, nearly one in four Americans will face elevated risks of cognitive decline and Alzheimer’s disease, highlighting the urgency for effective interventions to safeguard cognitive health. In response to this pressing concern, the COSMOS study led by researchers at Mass General Brigham, showed again the efficacy of multivitamin supplementation in preserving cognitive function.

Published in The American Journal of Clinical Nutrition, the study titled “Effect of multivitamin-mineral supplementation versus placebo on cognitive function: Results from the clinic sub-cohort of the COSMOS randomized clinical trial and meta-analysis of three cognition studies within COSMOS” presents compelling evidence in favor of daily multivitamin intake.
Building upon previous findings, this comprehensive analysis reveals consistent and statistically significant enhancements in both memory and overall cognitive function among individuals consuming multivitamins daily, compared to a placebo.

Dr. Chirag Vyas, lead author and faculty member at Massachusetts General Hospital, underscores the significance of these findings, stating, “Cognitive decline ranks high among the concerns of older adults. Daily multivitamin supplementation presents a promising avenue to mitigate cognitive aging.”
In the COSMOS-Clinic arm of the study, detailed in-person cognitive evaluations over 2 years with, a meta-analysis incorporating findings from three separate studies within COSMOS demonstrated robust evidence supporting the cognitive benefits of multivitamin supplementation, estimating a potential delay in cognitive aging by approximately two years compared to a placebo.

Brain & Body Nutrition You Need Every Day

The patented MDR Fitness Tabs promote cognitive and overall health from head to toe with a comprehensive array of nutrients, each contributing to peak wellness and vitality:

• Vitamin A: Supports vision health and acts as a potent antioxidant.
• Vitamin C: Enhances immune function, promotes collagen synthesis, and aids in iron absorption.
• Vitamin E: Safeguards cellular membranes, supports heart health, and acts as an antioxidant.
• Beta Carotene: Precursor to Vitamin A, supports immune and eye health.
• Zinc: Vital for immune function, wound healing, and DNA synthesis.
• Magnesium: Regulates muscle and nerve function, supports bone mineralization, contributes to cardiovascular health and is needed for over 300 metabolic reactions in the body.
• Calcium: Essential for bone density, blood pressure support and muscle function.
• Selenium: Acts as a potent antioxidant, supports thyroid and prostate health, and guards against cellular damage.
• Chromium: Aids in glucose metabolism, supports balanced blood sugar levels, and facilitates energy production.
• Lycopene: Derived from LycoMato® tomatoes, bred to be rich in a potent antioxidant that supports heart health, youthful skin, prostate function and more.
• Lutein: Supports eye health, filters harmful blue light, combats age-related macular degeneration and helps shield skin from environmental damage.
• Vitamin D: “The sunshine vitamin” aids calcium absorption to build strong bones, supports immune function, and promotes overall health. Scientists from Tufts University also found that Vitamin D may affect our brain’s cognitive function. (2)

In a study published in Alzheimer’s and Dementia: the Journal of the Alzheimer’s Association (2), researchers found that higher levels of vitamin D in brain tissue were associated with better cognitive function—a stronger memory and a slower progression of cognitive decline.

Where some studies highlight the role of a specific vitamin, like Vitamin D for brain health, the symphony of nutrients provided by a balanced diet supplemented with MDR Fitness Tabs forms a robust shield against deficiencies with additional critical nutrients for maximum daily results.

With one AM Fitness Tab to jump-start your day, and a nuturing PM Fitness Tabs each afternoon to replenish what our lifestyle and metabolism deplete, MDR Fitness Tabs is the key to a lifetime of good health. From bolstering immune function to safeguarding cognitive health, each nutrient especially selected by Medical Doctors Researach plays a pivotal role in nurturing your body and mind, so you can thrive and embrace life to the fullest.

We’re so sure MDR Fitness Tabs will make such an important difference in your life, we’ll give you a free off-grid Survival Radio just for trying them!
​
• Sharp thinking
• Well-Being
• Good Health

With just one MDR Fitness Tabs in the morning, and one in the afternoon you can feel more energized, focused, and able to live life to the fullest with maximum health and vitality.

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References

1. Vyas, C., Manson, J., Sesso, H., Okereke, O., et al. (2024). “Effect of multivitamin-mineral supplementation versus placebo on cognitive function: Results from the clinic sub-cohort of the COSMOS randomized clinical trial and meta-analysis of three cognition studies within COSMOS.” *American Journal of Clinical Nutrition*. doi: [10.1016/j.ajcnut.2023.12.011](https://doi.org/10.1016/j.ajcnut.2023.12.011).

2. Shea, M. Kyla, Kathryn Barger, Bess Dawson-Hughes, Sue E. Leurgans, Xueyan Fu, Bryan D. James, Thomas M. Holland, Puja Agarwal, Jifan Wang, Gregory Matuszek, Nicholas E. Heger, Julie A. Schneider, and Sarah L. Booth. “Brain vitamin D forms, cognitive decline, and neuropathology in community-dwelling older adults.” *Alzheimer’s & Dementia*, vol. 19, no. 6, 07 December 2022.

New Study Finding- Excess Niacin May Harm Heart Health 22 Feb 2024, 11:00 am

Niacin, also known as Vitamin B3, is an essential nutrient for good health. It also has long been utilized as a treatment to manage high cholesterol levels, when taken in high dosages. It is no longer the most popular cholesterol lowering option because of its side effects like skin flushing, upset stomach, liver toxicity, and increased blood sugar levels. Now scientists have discovered another problem from taking megadoses of Niacin…

A groundbreaking study led by Dr. Stanley Hazen, Chair of Cardiovascular and Metabolic Sciences at Cleveland Clinic’s Lerner Research Institute, has revealed a link between excess niacin consumption and an increased risk of heart attacks and strokes. Excess niacin creates a byproduct called 4PY, which is strongly associated with vascular inflammation and the development of conditions like atherosclerosis, which can ultimately contribute
to heart disease. (1)

With normal dietary intake, or reasonable supplementation, Niacin does have great health value! Known as Vitamin B3, it is essential for more than 400 crucial enzymes, when converted in the body to its metabolically active form —nicotinamide adenine dinucleotide (NAD). Anti-aging research scientists are even recommending infusions of NAD to help stall some of the effects of aging.

If you already take MDR Fitness Tabs, or Stress Defense Tabs, you are getting proper levels of Vitamin B3, in the gentle to take form, niacinamide, plus vital nutrients like Calcium and Vitamin D for bone health, Vitamin C, Beta Carotene and Vitamin E for immune support, Vitamin B12 and Magnesium for energy production and over 20 key nutrients for healthy longevity.
If you have heart issues, you can also benefit from our patented formula called MDR Heart Tabs.

Developed by George Christakis, M.D., the MDR Heart Tabs formula is designed for anyone with heart concerns, and for those over 50, who want to stay youthful and healthy.

MDR Heart Tabs provide a niacin-free formula enriched with essential heart-healthy nutrients, such as Carnitine, Folic Acid, Vitamin B6, Vitamin B12, and Quercetin.

Love Your Heart with MDR Heart Tabs

Some of the benefits of key nutrients in Heart Tabs:

• Carnitine aids in the transportation of fatty acids into cells for energy production.

• Co-Enzyme Q10 assists in cellular energy production vital to the heart and kidneys where energy demands are high. It also helps counteract the muscle damage, that may be caused by use of statins for cholesterol management.

• Folic Acid, Vitamin B6, and Vitamin B12 support healthy homocysteine levels, which are linked to heart health.

• Quercetin acts as an antioxidant and anti-inflammatory compound, helping to protect the heart from oxidative stress and inflammation.

The patented Heart Tabs formula contains nutrients that specifically support cardiovascular function, circulation, and antioxidant defenses, all supported by scientific rationale.

Just one tablet a day can help you or a loved one to enjoy a better quality of life, with greater vitality, and cardiovascular health.

Try MDR Heart Tabs for a month and feel the difference!

References

1. Ferrell, M., Wang, Z., Anderson, J.T. et al. A terminal metabolite of niacin promotes vascular inflammation and contributes to cardiovascular disease risk. Nat Med 30, 424–434 (2024)

2. National Institutes of Health – Office of Dietary Supplements. (n.d.). Niacin – Health Professional Fact Sheet. Retrieved from https://ods.od.nih.gov/factsheets/Niacin-HealthProfessional/

Are Fish Oil Capsules Safer than Fish? 20 Feb 2024, 3:56 pm

Nutritionists usually recommend we try to get most of our nutrients from a healthy diet and add supplements to fill in the gaps. As people try to follow a healthy lifestyle, many choose to eat more fish instead of meats. Unfortunately, research published in the American Journal of Cardiology warns that large amounts of fish consumption can increase exposure to environmental toxins such as polychlorinated biphenyls, dioxins, and other contaminants like mercury. Farm raised fish may also contain unwanted toxins. Over the years the buildup of heavy metals can damage damage the brain and nervous system, which can be even more harmful for children and pregnant women. When you eat seafood containing mercury, about 95 percent is absorbed, and moves into your bloodstream where it can penetrate cells and damage any tissue or organ.

Fish with the highest mercury levels include swordfish, shark, gulf tilefish, grouper, marlin, mackerel, orange roughy, tuna, and sea bass, so don’t eat them often.

A 6-ounce serving of salmon contains about 4 micrograms of mercury vs. 60 micrograms for the same portion of canned albacore tuna—and 170 micrograms for swordfish. Consumer Reports thinks pregnant women should not eat any tuna so definitely avoid swordfish.

You can find the mercury content of your favorite fish on here:

http://www.stonybrook.edu/commcms/gelfond/docs/Seafood%20Mercury%20Database.pdf

If you eat locally caught fish, check advisories for PCBs or other seafood contaminants. If no current local fish-advisory information exists, federal officials recommend that adults eat no more than 6 ounces per week. For children under the age of 6 years old, the recommended limit is 1 to 2 ounces per week, for 6-to-12-year-olds, the limit is 2 to 3 ounces per week. (All these groups should avoid eating any other type of fish that week.)

You can get the daily health benefits of omega-3 fatty acids, without the risks of heavy metals by taking a quality fish oil supplement. MDR OlivOmega is derived from the finest oils, derived from pristine waters- molecularly distilled so environmental toxins and unwanted compounds are removed. Plus, the oil is protected from rancidity with an infusion of antioxidants so each capsule delivers pure fresh fish oil rich in EPA and DHA for good health.

References

https://www.ncbi.nlm.nih.gov/pubmed/17368277

https://www.consumerreports.org/cro/magazine/2014/10/can-eating-the-wrong-fish-put-you-at-higher-risk-for-mercury-exposure/index.htm

Nature’s Sweet Cough Remedy for Adults and Kids 31 Jan 2024, 9:38 pm

Are you dealing with a troublesome cough? Whether you’re an adult with a nagging cough, or a concerned parent wanting to speed your child’s recovery, sometimes nature offers the easiest remedies. In this case, honey and pineapple might offer sweet solutions to an irritating problem.

Coughing can be a real nuisance, often caused by self-limiting viral infections of the airways. When other symptoms are present, like fever, shortness of breath or body aches, seeking prompt medical care is important.

Natural Remedies: Honey and Pineapple

For generations before we had the convenience of local pharmacies and prescription medications, the use of natural and herbal products for cough relief were the only help available.

The Healing Powers of Honey

Honey has a long history of being used as a natural remedy for coughs and upper respiratory tract infections. The World Health Organization recognizes honey as a potential treatment for cough in children, citing its numerous beneficial properties, including antioxidant, antibacterial, antifungal, antiviral, and anti-inflammatory.

Dextromethorphan and diphenhydramine are often used as antitussive agents. In one interesting study (1), in children with irritative nocturnal coughs, honey (2.5mL) administered before sleep, showed better results regarding symptom relief when compared with these two popular drugs.

Combining Pineapple Extract and Honey

Pineapple extract, rich in Bromelain- a group of enzymes found in pineapple plants, has also been shown to have anti-inflammatory and mucolytic effects, helping to dissolve bronchial secretions, and decrease neutrophil migration to sites of inflammation.

In a double-blind, randomized study (2) involving two groups of children- aged between two and 15 years with irritative cough, the active group received a combination of Buckwheat honey and pineapple extract, rich in Bromelain as a syrup formulation, while the placebo group received only honey. (Before the randomization, patients with detectable bronchospasm were prescribed specific medications and considered ineligible for the study.)

The Results

The study found that both groups showed a reduction in coughing episodes and cough score 30 minutes after administration. The study suggests that honey alone may have a therapeutic effect on mucus and cough characteristics, and adding pineapple bromelin also is beneficial.

In conclusion, nature has bestowed us with the healing powers of honey and pineapple. These nutritious natural remedies offer a sweet way to help combat nagging coughs in both children and adults.

Note: The next time, you are fighting a cold or cough, remember to get plenty of rest, follow your doctor’s recommendations, eat chicken soup, breathe steam with sliced garlic and ginger, drink tea with lemon and honey, and take anti-viral nutritional supplements like OnGuard Immune Defense. MDR offers clinically proven and immune-active Maitake and Shiitake Mushrooms combined with Colostrum and Lo Han to help support your immune defenses so you can knock out what ails you, and get back to feeling good again!

You can buy OnGuard Now Here!

References

1. Shadkam M, Mozaffari-Khosravi H, Mozayan MR. A comparison of the effect of honey, dextromethorphan, and diphenhydramine on nightly cough and sleep quality in children and their parents. J Altern Complement Med. 2010;16:787–793.

2. Peixoto DM, Rizzo JA, Schor D, Silva AR, Oliveira DC, Solé D, Sarinho E. Use of honey associated with Ananas comosus (Bromelin) in the treatment of acute irritative cough. Rev Paul Pediatr. 2016 Oct-Dec;34(4):412-417

3. Fitzhugh DJ, Shan S, Dewhirst MW, Hale LP. Bromelain treatment decreases neutrophil migration to sites of inflammation. Clin Immunol. 2008;128:66–74.

4. Müller S, März R, Schmolz M, Drewelow B, Eschmann K, Meiser P. Placebo-controlled randomized clinical trial on the immunomodulating activities of low- and high-dose bromelain after oral administration-new evidence on the anti-inflammatory mode of action of bromelain. Phytother Res. 2013;27:199–204.

5. Seltzer AP. Adjunctive use of bromelains in sinusitis: a controlled study. Eye Ear Nose Throat Mon. 1967;46:1281–1288.

6. Taub SJ. The use of bromelains in sinusitis: a double-blind clinical evaluation. Eye Ear Nose Throat Mon. 1967;46:361–362.

7. Ako H, Cheung AH, Matsuura PK. Isolation of a fibrinolysis enzyme activator from commercial bromelain. Arch Int Pharmacodyn Ther. 1981;254:157–167.

8. Braun JM, Schneider B, Beuth HJ. Therapeutic use, efficiency and safety of the proteolytic pineapple enzyme Bromelain in children with acute sinusitis in Germany. In Vivo. 2005;19:417–421.

9. Cohen HA, Rosen J, Kristal H, Laks Y, Berkovitch M, Uziel Y, et al. Effect of honey on nocturnal cough and sleep quality: a double-blind, randomized, placebo-controlled study. Pediatrics. 2012;130:465–471.

10. Paul IM, Beiler J, McMonagle A, Shaffer ML, Duda L, Berlin CM, Jr. Effect of honey, dextromethorphan, and no treatment on nocturnal cough and sleep quality for coughing children and their parents. Arch Pediatr Adolesc Med. 2007;161:1140–1146.

11. Evans H, Tuleu C, Sutcliffe A. Is honey a well-evidenced alternative to over-the-counter cough medicines? J R Soc Med. 2010;103:164–165.

12. ER, Carson WF, Singh A, Pensa M, Guernsey LA, Schramm CM, et al. Oral bromelain attenuates inflammation in an ovalbumin-induced murine model of asthma. Evid Based Complement Altern Med. 2008;5:61–69.

13. Paul IM, Yoder KE, Crowell RK, Shaffer ML, McMillan HS, Carlson MC, et al. Effect of dextromethorphan, diphenhydramine and placebo on nocturnal cough and sleep quality for coughing children and their parents. Pediatrics. 2004;114:e80–e85.

Combating Muscle Loss with Aging 18 Jun 2023, 3:49 am

As we age, our bodies undergo many changes, and one of the most significant concerns is the loss of muscle mass and strength, a condition known as sarcopenia. Sarcopenia affects a large portion of the older folks and can have detrimental effects on health and quality of life.

Here are five exercises which can be performed from either a standing or sitting position to help you maintain muscles:

1. Squats: Stand with your feet shoulder-width apart and slowly lower yourself into a sitting position and push back up to a standing position. You can do this over a chair for safety. This exercise targets your lower body muscles, including the quadriceps, hamstrings, and glutes.

2. Seated Rows: Sit on a chair or bench with your back straight and legs extended in front of you. Hold a resistance band or cable handles with your arms extended. Pull your elbows back, squeezing your shoulder blades together. This exercise targets the muscles in your back and arms.

3. Standing Calf Raises: Stand with your feet shoulder-width apart, rise up onto the balls of your feet, and then slowly lower your heels back down. This exercise primarily targets the calf muscles. (Lean on a table for balance, if needed)

4. Standing Shoulder Press: Hold a pair of dumbbells or a resistance band with your palms facing forward. Lift the weights up to shoulder level, then press them overhead until your arms are fully extended. Lower the weights back down to shoulder level. This exercise targets the shoulder muscles.

5. Seated Leg Extensions: Sit on a chair or bench with your back straight and legs extended in front of you. Place your hands on the sides of the chair for support. Lift one leg up, straightening it in front of you, and then lower it back down. Alternate between legs. This exercise targets the quadriceps muscles.

Now, let’s move on to five foods that can help build muscle:

1. Lean meats: Chicken breast, turkey, lean cuts of beef, and fish are excellent sources of high-quality protein, which is essential for muscle growth and repair.

2. Eggs: They are packed with protein, healthy fats, and essential vitamins and minerals. Eggs also provide all the essential amino acids needed for muscle building.

3. Greek yogurt: It is rich in protein and contains beneficial probiotics. Greek yogurt is a versatile food that can be enjoyed alone or used as a base for smoothies and desserts.

4. Quinoa: This whole grain is a complete protein source, meaning it contains all the essential amino acids. It also provides fiber and other nutrients for overall health.

5. Nuts and seeds: Almonds, walnuts, chia seeds, and flaxseeds are excellent sources of protein, healthy fats, and micronutrients. They can be added to meals, snacks, or smoothies.

The recommended daily protein intake for adults to maintain muscle mass varies depending on factors such as age, sex, weight, and your activity level. A football player needs a lot more then a petite sedentary woman. A general guideline is to consume 0.8 grams of protein per kilogram of body weight. This means that if you weigh 70 kilograms (154 pounds), you would aim for about 56 grams of protein per day.

Unlocking the Power of Amino Acids and Secretagogues for Enhanced HGH and Muscle Synthesis

Recent research has shed light on other interventions to help counteract muscle loss, with a focus on amino acids and secretagogues that enhance human growth hormone (HGH) production and muscle synthesis.

Sarcopenia is a complex process influenced by various factors, including hormonal changes, reduced physical activity, inadequate nutrition, and impaired muscle protein synthesis. With age, the levels of anabolic hormones, such as HGH, testosterone, and insulin-like growth factor 1 (IGF-1), tend to decline, leading to anabolic resistance and impaired muscle tissue regeneration.

Amino acids are the fundamental components of proteins and play a crucial role in muscle growth and repair. Essential amino acids (EAAs), including leucine, isoleucine, and valine, are particularly important for stimulating muscle protein synthesis. Leucine, in particular, acts as a potent activator of the mammalian target of rapamycin (mTOR) pathway, which triggers muscle protein synthesis.

Supplementation with EAAs has shown promising results in preserving muscle mass and function in older individuals. Studies have demonstrated that a balanced blend of EAAs, especially when consumed in conjunction with resistance exercise, can enhance muscle protein synthesis, stimulate muscle recovery, and attenuate age-related muscle loss.

Secretagogues are substances that stimulate the production and release of hormones. In the context of muscle preservation, secretagogues that enhance HGH production have garnered significant attention. They can promote muscle protein synthesis, increase lean body mass, and improve physical performance.

Certain amino acids, such as arginine, ornithine, glutamine, glycine and lysine, have been identified as potent secretagogues, stimulating the release of HGH from the pituitary gland. When combined in specific ratios and administered orally or intravenously, these amino acids can promote the release of HGH, contributing to improved muscle mass and strength.

Additionally, some natural compounds and synthetic peptides, known as growth hormone secretagogues (GHSs), have shown promise in stimulating HGH production. These substances work by binding to specific receptors in the brain, triggering the release of HGH. GHSs, such as growth hormone-releasing peptides (GHRPs) and growth hormone-releasing hormone analogs (GHRHAs), have demonstrated potential in combating muscle loss and improving body composition in the elderly.

Muscle loss with aging is a significant concern that can have far-reaching consequences for an individual’s overall health and well-being. However, recent advancements in the field of nutrition and endocrinology have shed light on potential interventions to counteract sarcopenia. Amino acids, particularly essential amino acids, act as the building blocks of muscle and can enhance muscle protein synthesis when combined with resistance exercise. Moreover, secretagogues have shown promise in enhancing HGH production and stimulating muscle synthesis.

MDR VitalFactors is a nutritional approach that utilizes secretagogues to help enhance natural HGH release. The effervescent formula also supports natural vitality, brain function, heart health, immune defenses and overall good health. Check it out at VitalFactors.com or call 800 637 8227 to reach MDR.com.

From healing a painful bone break to wearing high heels. How this Hollywood Celebrity recovered fast. 1 Jan 2023, 9:48 pm

Two-time Academy Award-nominated Singer/Songwriter, Carol Connors, is singing a happy tune thanks to MDR Chondro-Pro. Patricia Riley, Founder of MDR, introduced her to this nutritional formula after she broke her ankle and was suffering from pain. “Don’t expect to ever wear high heels again,” her Doctor said. That’s when Patricia met Carol at a Hollywood charity event, with her foot in a cast. Pat sent her Chondro-Pro from MDR and she started taking 3 capsules each day. Then it was time for her next Doctor’s appointment. Carol was healing so fast that he asked her if she was bionic. He even skipped the last X-ray. To his amazement, Carol was back in high heels and waterskiing just a few months later! Pat and Carol became good friends and decades later CC, as her friends call her, still hikes in the mountains, scuba dives in the ocean, and is seen dressed to the nines in her 5-inch heels at Hollywood events. CC raves about how good she feels and still takes 3 capsules of Chondro-Pro each day to nourish her joints so she can maintain an active life! It also keeps her skin youthful looking! After co-writing “Gonna Fly Now”, the theme from “Rocky”, CC believes we can all triumph over adversity! Why settle for ankle pain when we have a winning solution… Chondro-Pro!

Chondro-Pro promotes joint comfort and health.

Probiotic Imbalance Linked to Asthma 22 Mar 2018, 9:13 pm

In recent research, an imbalance in the microbiome (human gut bacteria), has been implicated in conditions such as diabetes and schizophrenia. A team of researchers led by University of Alberta microbiome epidemiologist Anita Kozyrskyj set out to look at the interaction between gut bacteria and asthma during pregnancy. The researchers recruited 1,000 mothers and their infants. At 3-4 months of age, the infants’ fecal microbiota was assessed and compared with samples from mothers without asthma.

Kozyrskyj reported, “We saw a significant reduction in the family of microbes called Lactobacillus in Caucasian baby boys born to pregnant women who had asthma, and this was especially evident if the asthmatic mother had allergies or was overweight.”

This may imply that conditions like asthma, allergies, and the tendency to be overweight may be influenced by the individual’s microbiome. In the future probiotic treatments to restore proper gut flora may be an accepted part of preventive medicine.

Reference

http://erj.ersjournals.com/content/50/5/1700280.fu…